Genetic Determinants of Obesity

Genes are responsible for affecting the amount and types of food that we prefer to eat. We all have noticed that some people stay thin whatever they seem to eat and some become obese. Research shows that obesity tends to run in families and studies with twins and adopted children have shown that genes play a key role in this. Genome-wide association studies examine hundreds and thousands of genetic markers across thousands of individuals’ complete sets of DNA to find gene variations that may cause a particular disease. Numerous genetic association studies have been recorded, but only a few have been successfully replicated. Large studies and new research tools will advance us to an understanding of the different genes and their interactions to cause obesity, which may help guide successful interventions and treatments. 

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